Genetic Factors in Parkinson’s Disease
نویسنده
چکیده
A mutation first described in the Italian Contrusi family’s SNCA gene, encoding the protein alpha-synuclein, was described in 1990. At the same time, it was first described as a mutation in Parkinson's disease. However, in 1998 the first described mutation in the PRKN gene encoding the Parkin protein was found. The turn of the XXI has seen a breakthrough in the study of the genetic determinant of Parkinson's disease. A number of genes associated with the onset of familial Parkinson's disease and/or responsible of labeled PARK have been described.
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عنوان ژورنال:
دوره 14 شماره
صفحات -
تاریخ انتشار 2013